Non-alkaloid constituents of Vinca major / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 56-60, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-812450
ABSTRACT
The present study was designed to investigate the non-alkaloid compounds from the leaves and stems of Vinca major cultivated in Yunnan Province, China. The compounds were isolated using chromatographic techniques. The structures were elucidated by 1D- and 2D-NMR spectroscopic methods in combination with UV, IR, and MS analyses. The 1, 1-diphenyl-2-picrylhydrazyl (DPPH)-scavenging activity of Compounds 1-7 were evaluated. One new iridoid glycoside (compound 1), together with 11 known compounds, were isolated from Vinca major. Compounds 1, 5, and 6 showed moderate DPPH-scavenging activity, with IC50 values being 70.6, 32.8, and 62.2 μmol·L(-1), respectively. In conclusion, compound 1 is a newly identified iridoid glycoside with moderate antioxidant activity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Química
/
Tallos de la Planta
/
Hojas de la Planta
/
Vinca
/
Glicósidos Iridoides
/
Antioxidantes
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2016
Tipo del documento:
Artículo
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