Targeting EGFRvIII for treatment of glioblastoma: From molecular mechanisms to clinical strategies / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1281-1286, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-813018
ABSTRACT
Glioblastoma is one of the most common intracranial malignant tumor and its initiation and progression are closely associated with epidermal growth factor receptor (EGFR). EGFR variant III (EGFRvIII) is a mutant EGFR and highly expressed in glioblastoma. EGFRvIII promotes the proliferation and invasiveness of glioblastoma cells and induces drug resistance by signaling networks.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Encefálicas
/
Transducción de Señal
/
Glioblastoma
/
Línea Celular Tumoral
/
Quimioterapia
/
Receptores ErbB
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS