Biological roles of adenosine deaminase acting on RNA and their relationship with human diseases / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 904-911, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-813176
ABSTRACT
RNA editing, especially A-to-I RNA editing, is a common post-transcriptional modification in mammals. Adenosine deaminase acting on RNA (ADAR) is a key protein for A-to-I editing, which converts the adenosine group of a double-stranded RNA to creatinine group by deaminating it, resulting in a change of nucleotide sequence. There are 3 types of ADARs (ADAR1, ADAR2, ADAR3) that have been found in recent years. The abnormalities of ADARs are closely related to many human diseases such as viral infections, metabolic diseases, nervous system diseases, and tumors.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
ARN Bicatenario
/
Secuencia de Bases
/
Adenosina
/
Adenosina Desaminasa
/
Enfermedad
/
Proteínas de Unión al ARN
/
Edición de ARN
/
Creatinina
/
Desaminación
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2018
Tipo del documento:
Artículo
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