Current status for animal models of intensive care unit acquired muscle weakness / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 691-696, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-813209
ABSTRACT
Intensive care unit acquired muscle weakness (ICU-AW) is a neuromuscular complication secondary to severe illness. The essence for this disease is skeletal muscle dysfunction. With the development of medical technology, the survival rate for severe patients has been significantly improved. The long term complications for the severe patients with ICU-AW are getting more and more common, and they seriously affect the quality of life and prognosis of patients. However, the current treatment is ineffective. Establishment of ICU-AW animal model is an important way to study the pathogenesis and intervention targets for this disease. There are many risk factors for this disease, and the principles for ICU-AW animal models are not the same at home and abroad, and the methods of preparation are different. The choice of a reasonable animal model is important for the reliability of the results.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Calidad de Vida
/
Tasa de Supervivencia
/
Reproducibilidad de los Resultados
/
Mortalidad
/
Enfermedad Crítica
/
Músculo Esquelético
/
Debilidad Muscular
/
Modelos Animales de Enfermedad
/
Unidades de Cuidados Intensivos
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2018
Tipo del documento:
Artículo
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