Clinical observation and follow-up of 186 cases of Kawasaki disease with lesion of coronary artery / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To provide a reference for diagnosing and treating Kawasaki disease (KD).@*METHODS@#We retrospectively analyzed the clinical data of 186 cases of final diagnosed Kawasaki disease and observed the characteristics of incomplete KD.@*RESULTS@#There were 108 cases of KD with lesion of coronary artery in 186 cases through 2-dimensional echocardiography. The incidence rate was 58.1%; it was easier to complicate with lesion of coronary artery in incomplete KD. Of them, slight coronary artery aneurysm was 60 cases (55.6%), midrange coronary artery aneurysm was 36 cases (33.3%), and severe coronary artery aneurysm was 12 cases (11.1%). After 1 to 3 year's follow-up to all cases, the cases of slight coronary artery aneurysm all recovered in 6 months. The state of an illness in the cases of moderate and heavy coronary artery aneurysm was improved in 6 months except 3 huge aneurysm combining coronary artery thrombosis and coronary artery stenosis developed heart infarction and cardiomyopathy. The 30 cases of coronary artery aneurysm recovered in 1 year, 8 cases in 2 years, and 7 cases in 3 years. The patient that were not found with arterial coronary at the acute stage had no abnormality in 1 to 2 years after the treatment.@*CONCLUSION@#It is easier to complicate with lesion of coronary artery in incomplete KD and the prognosis of coronary aneurysm is worse. To improve early diagnose and treatment of incomplete KD, it is necessary to use 2-dimensional echocardiography to check the suspected cases.