Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1129-1131, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-814139
ABSTRACT
OBJECTIVE@#To evaluate the efficacy and safety of 4 kinds of triple strategy of Helicobacter pylori (Hp) eradication.@*METHODS@#A total of 307 patients who suffered from Hp infection, confirmed by rapid urease test (RUT) and 14C-urea breath test (UBT),were randomly divided into 4 groups. Each group had 80, 76, 77, and 74 patients respectively. Group A was treated with rabeprazole, clarithromycin, and furazolidone (RCF); Group B with ranitidine bismuth citrate, clarithromycin, and furazolidone (BCF); Group C with rabeprazole, amoxicillin, and furazolidone (RAF); while Group D with ranitidine bismuth citrate, amoxicillin, and furazolidone (BAF). Hp was detected by RUT and UBT at 4 weeks after later treatment.@*RESULTS@#Hp eradication rates of group A,B,C, and D were 90.0%,67.1%,62.3%,and 45.9%,respectively. The difference between Group A and Group B, Group A and Group C was significant (P<0.05). Eradication rate of Group B and C was higher than that of Group D (P<0.05). There was no statistical difference between the eradication rate of Group B and C, and among the side effects of the 4 groups.@*CONCLUSION@#The strategy of RCF was the best among the 4 triple strategy of Hp eradication, which can be used clinically.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Úlcera Gástrica
/
Helicobacter pylori
/
Infecciones por Helicobacter
/
Claritromicina
/
Quimioterapia
/
Quimioterapia Combinada
/
Úlcera Duodenal
/
2-Piridinilmetilsulfinilbencimidazoles
/
Rabeprazol
/
Furazolidona
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2008
Tipo del documento:
Artículo
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