Treatment of brain injured rats through transplanting amniotic-derived mesenchymal stem cells in different ways / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 926-930, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-814174
ABSTRACT
OBJECTIVE@#To compare the behavioral improvement to find the best transplantation approach for treating brain injury through transplanting amniotic-derived mesenchymal stem cells into brain injured rats in different ways.@*METHODS@#Eighty brain injured Wista rats were randomly divided into a control group with brain injury alone (n=20) and a treatment group(n=60) which were further evenly divided into Group A (transplanted through the vena caudalis), Group B (transplanted through the ventriculus cerebri lateralis), and Group C (transplanted through the injured brain area). Each group was transplanted with amniotic-derived esenchymal stem cells, and their therapeutic efficacy would be evaluated through the neurological severity score (NSS).@*RESULTS@#Compared with other groups, the behaviors of Group C had markedly improved. There was statistically significant difference in the 2 groups (P0.05).@*CONCLUSION@#Transplanting the amniotic-derived mesenchymal stem cells into the injured brain area may be effective for brain injury in rats.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Terapéutica
/
Lesiones Encefálicas
/
Distribución Aleatoria
/
Ratas Wistar
/
Biología Celular
/
Trasplante de Células Madre Mesenquimatosas
/
Células Madre Mesenquimatosas
/
Amnios
/
Métodos
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2008
Tipo del documento:
Artículo
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