Effect of antipsychotic drugs on life quality of schizophrenic patients: one year follow-up study / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 850-855, 2009.
Article
en Zh
| WPRIM
| ID: wpr-814209
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To compare the effect of 7 antipsychotic drugs on the life quality of schizophrenia patients including chlorpromazine, sulpiride, clozapine, risperidone, olanzapine, quetiapine, and aripiprazole.@*METHODS@#A total of 1,227 stable schizophrenic patients within 5 years onset who took 1 of the 7 study medications as maintenance treatment were followed up for 1 year at 10 China sites. Patients were evaluated by the short form-36 health survey (SF-36) at the baseline and at the end of 1 year.@*RESULTS@#The life quality was improved obviously at the end of the follow-up. There was significant difference in body pain, vitality, and mental health (P<0.05) among these antipsychotic drugs.@*CONCLUSION@#All 7 antipsychotic drugs can improve the life quality of schizophrenia patients. Atypical antipsychotic drugs, especially olazapine and quetiapine, are superior to typical antipsychotic drugs in improving life quality.
Texto completo:
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Índice:
WPRIM
Asunto principal:
Calidad de Vida
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Esquizofrenia
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Antipsicóticos
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Benzodiazepinas
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Encuestas y Cuestionarios
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Estudios de Seguimiento
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Usos Terapéuticos
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Dibenzotiazepinas
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Quimioterapia
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Fumarato de Quetiapina
Tipo de estudio:
Observational_studies
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Prognostic_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Año:
2009
Tipo del documento:
Article