Effect of exogenous fat on bone mineral density by DXA / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To observe the effect of exogenous fat on the bone mineral density (BMD) of lumbar spine (LS) on a phantom measured by dual energy X-ray absorptiometry (DXA) Hologic QDR4500A.@*METHODS@#LS DXA scans were performed on an LS phantom, and were repeated when with lard packets (2 fresh lard packets and 2 refined lard packets, 5 cm or 10 cm thick).@*RESULTS@#After fresh lard packets were placed, only L1 BMD decreased significantly (P<0.05).When the 5 cm-thick refined lard packet was placed, BMD, bone mineral content (BMC),and bone area (BA) decreased obviously, but with the 10 cm-thick refined lard packet, BMD, BMC and BA decreased significantly (P<0.05 or P<0.01).@*CONCLUSION@#The exogenous fat may affect LS BMD of lumbar spine phantom by DXA Hologic QDR4500A, with significant decrease of the value,which may cause anomaly measurement of BMD in obese people and even misdiagnosis of osteoporosis.