Sex difference in performance in elevated plus maze and hippocampal GluR1 level / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 750-753, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-814528
ABSTRACT
OBJECTIVE@#To explore whether sex difference exists in the performance in each arm of elevated plus maze (EPM) and GluR1 level in the hippocampus of female and male Sprague-Dawley rats.@*METHODS@#Eleven male and 10 female SD rats were tested for 5 minutes in the EPM. These rats were decapitated 30 min after testing. The left and right hippocampus were dissected. Samples were stored at -80 degree for protein extracting. Western blot was used to detect the GluR1 levels in the hippocampus.@*RESULTS@#Female rats exhibited less anxiety-like behaviors than male rats in the EPM (P<0.05).Female rats had lower GluR1 levels in total and left hippocampus than those of male rats (P<0.05).@*CONCLUSION@#Sex difference exists between female and male rats in the EPM and hippocampal GluR1.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ansiedad
/
Fisiología
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Conducta Animal
/
Caracteres Sexuales
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Ratas Sprague-Dawley
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Receptores AMPA
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Aprendizaje por Laberinto
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Hipocampo
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Metabolismo
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2011
Tipo del documento:
Artículo
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