Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese Han population / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1141-1145, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-814810
ABSTRACT
OBJECTIVE@#To explore the relationship between ABCC11 gene single nucleotide polymorphism (SNP) and the incidence of axillary osmidrosis in Chinese Han population.@*METHODS@#The genotype of ABCC11 gene SNP at rs17822931 in 40 patients with axillary osmidrosis and 5 normal Han people was detected and analyzed by high resolution melt and gene sequencing.@*RESULTS@#The detection of the genotype of ABCC11 gene SNP at rs17822931 showed that 37 of the 40 patients were GA genotype and the other 3 were GG genotype, while the 5 normal subjects were AA genotype.@*CONCLUSION@#SNP in ABCC11 is the genetic cause of axillary osmidrosis. GG or GA leads to axillary osmidrosis, while AA allele presents the absence of axillary osmidrosis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Axila
/
Enfermedades de las Glándulas Sudoríparas
/
Incidencia
/
Transportadoras de Casetes de Unión a ATP
/
Polimorfismo de Nucleótido Simple
/
Pueblo Asiatico
/
Alelos
/
Frecuencia de los Genes
/
Genética
/
Genotipo
Tipo de estudio:
Estudio de incidencia
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2013
Tipo del documento:
Artículo
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