8.5 year-follow-up of combined heart-lung transplantation in a patient / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 212-215, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-814898
ABSTRACT
To summarize the case of combined heart-lung transplantation for a patient who survived for 8.5 years. On September 20, 2003, at Second Xiangya Hospital of Central South University, homologous heartlung transplantation was performed on a male patient who was diagnosed with cardiopulmonary failure secondary to congenital ventricular septal defect with severe pulmonary hypertension. Heart-lung allograft was preserved with 1500 mL modified St.Thomas solution and 3000 mL modified LPD solution. Postoperative immunosuppressive therapies included methylprednisolone and human anti-lymphocyte globulin protein in the induction period; and combination of ciclosporin A, CellCept and prednisolone in the stable period. In 2007, the treatment was changed to CellCept mg, twice a day+FK506 4 mg, twice a day. The patient lived 8.5 years of normal life with cardiac function of NYHA I-II. Echocardiogram showed left ventricular ejection fraction of 61% to 74%. Heart-lung transplantation proved reliable therapy modality for terminal cardiopulmonary failure. Excellent donor organ preservation and proper perioperative treatment are key factors for long-term survival after heart-lung transplantation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Cirugía General
/
Estudios de Seguimiento
/
Trasplante de Corazón-Pulmón
/
Usos Terapéuticos
/
Complejo de Eisenmenger
/
Rechazo de Injerto
/
Defectos del Tabique Interventricular
/
Hipertensión Pulmonar
/
Inmunosupresores
/
Métodos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2013
Tipo del documento:
Artículo
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