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Expression of lactate dehydrogenase-5 in non-Hodgkin lymphoma and its clinical significance / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 1312-1316, 2016.
Artículo en Chino | WPRIM | ID: wpr-815092
ABSTRACT
To determine expression of lactate dehydrogenase (LDH)-5 in non-Hodgkin lymphoma and its clinical significance.


Methods:

LDH-5 levels and LDH levels in NHL patients were examined by agarose gel electrophoresis and enzymatic method (n=63), respectively. Positive rates of LDH-5 and LDH were statistically analyzed.


Results:

The median age of NHL patients was 56(19-84) years old, including 36 males and 27 females. The positive numbers for LDH-5 and LDH in the initial treatment group (n=43) were significantly different (P0.05). In 15 cases under the status of progress, the difference of LDH-5 and LDH expressions were not significant (P>0.05), whereas the difference in cases of small B cell lymphoma was significant (P<0.05).


Conclusion:

LDH-5 can be used as an index for NHL to judge the tumor load and to predict the recurrence.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Sangre / Linfoma no Hodgkin / Biomarcadores de Tumor / Linfoma de Células B / Linfoma de Células T / Linfoma de Células B Grandes Difuso / Carga Tumoral / Lactato Deshidrogenasa 5 / Genética Tipo de estudio: Estudio pronóstico Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Central South University(Medical Sciences) Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Sangre / Linfoma no Hodgkin / Biomarcadores de Tumor / Linfoma de Células B / Linfoma de Células T / Linfoma de Células B Grandes Difuso / Carga Tumoral / Lactato Deshidrogenasa 5 / Genética Tipo de estudio: Estudio pronóstico Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Central South University(Medical Sciences) Año: 2016 Tipo del documento: Artículo