Expression of lactate dehydrogenase-5 in non-Hodgkin lymphoma and its clinical significance / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1312-1316, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-815092
ABSTRACT
To determine expression of lactate dehydrogenase (LDH)-5 in non-Hodgkin lymphoma and its clinical significance.
Methods:
LDH-5 levels and LDH levels in NHL patients were examined by agarose gel electrophoresis and enzymatic method (n=63), respectively. Positive rates of LDH-5 and LDH were statistically analyzed.Results:
The median age of NHL patients was 56(19-84) years old, including 36 males and 27 females. The positive numbers for LDH-5 and LDH in the initial treatment group (n=43) were significantly different (P0.05). In 15 cases under the status of progress, the difference of LDH-5 and LDH expressions were not significant (P>0.05), whereas the difference in cases of small B cell lymphoma was significant (P<0.05).Conclusion:
LDH-5 can be used as an index for NHL to judge the tumor load and to predict the recurrence.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Sangre
/
Linfoma no Hodgkin
/
Biomarcadores de Tumor
/
Linfoma de Células B
/
Linfoma de Células T
/
Linfoma de Células B Grandes Difuso
/
Carga Tumoral
/
Lactato Deshidrogenasa 5
/
Genética
Tipo de estudio:
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2016
Tipo del documento:
Artículo
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