Drug therapy for non-alcoholic fatty liver disease / 中国实用内科杂志

ABSTRACT

Non-alcoholic fatty liver disease(NAFLD) is the most common chronic liver disease in the world, but currently there are no approved effective drugs for NAFLD. At present, healthy diet and lifestyle intervention are the basic treatment for NAFLD, but drug therapy, mainly for metabolic syndrome and liver injury, is also essential. Currently, the commonly used drugs include hepatic protectant,insulin sensitizer, lipid-modulating drug, antioxidant, slimming drug, and intestinal probiotics, etc. A variety of new drugs targeting different pathogenesis of NAFLD have been put into clinical trials. In this paper, the current status of drug treatment and research on NAFLD in recent years was summarized.