The advances in diagnosis, treatment and clinical research of hepatocellular carcinoma in China / 中国实用外科杂志

ABSTRACT

As one of the high frequent malignancies in China,liver cancer has different disease background and clinicalmanagement modalities compared with that in foreigncountries. In recent years,China has made great progress inthe diagnosis and treatment of liver cancer. In the earlydiagnosis,a series of accomplishments have been achieved inliquid biopsy techniques represented by circulating micro RNA(mi RNA), circulating tumor cell(CTC),and circulating tumorDNA(ctDNA),which remarkably promoted the early diagnosis of liver cancer. In the surgical treatment,through continuousexploration of novel surgical methods,surgical indications andanti-recurrence and-metastasis strategies,patients get moresurgical opportunities,lower risks of metastasis and relapseand significantly prolonged overall survival. In addition,clinical research of liver cancer has received unprecedentedattention. The conclusions of some clinical trials have servedas important evidence to direct the development of guidelines,and to choose appropriate treatment strategies for patients inChina,which is more in line with the characteristics of livercancer in China.