Congenital diarrhea and enteropathies in children / 中国实用儿科杂志

ABSTRACT

Congenital diarrhea and enteropathies(CODEs)are typically monogenic disorders. Patients always present with persistent and severe chronic diarrhea. The diagnosis of CODEs is oftern delayed and there is a high mortality. Application of endoscopy,histologic evaluation and next generation sequencing might facilitate the diagnosis,and precision medicine to patients with CODEs.