Research progresses of Annexin A3 in malignant tumors / 医学研究生学报

ABSTRACT

Annexin A3(ANXA3), is a crucial member of the membrane associated protein superfamily, whose function research is still insufficient. Previous researches have confirmed that Annexin A3 is involved in a variety of cellular processes, but its function is still unclear. Accumulating evidences suggested that Annexin A3 is closely related to various malignant tumors, and plays an important role in tumor development, metastasis, invasion and drug resistance. Therefore, Annexin A3 is expected to be a new therapeutic target for malignant tumors. This article provided an overview about the role of Annexin A3 in malignant tumors.