Role of hepatic macrophages in the development and progression of primary biliary cholangitis / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 936-939, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-819202
ABSTRACT
Primary biliary cholangitis(PBC) is a chronic autoimmune liver disease characterized by cholestasis and has unknown etiology. Its specific pathogenesis remains unclear, but hepatic macrophages are one of the key aspects of the immune and inflammatory response of PBC and the injury of biliary epithelial cells. Hepatic macrophages are classified into resident Kupffer cells and monocyte-derived macrophages according to their source, and these cells play an important role in the development and progression of PBC. This article reviews the role of hepatic macrophages in the development and progression of PBC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Clinical Hepatology
Año:
2020
Tipo del documento:
Artículo
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