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In vitro evaluation of antimicrobial and antioxidant activities of methanolic extract of Jasminum humile leaves
Asian Pacific Journal of Tropical Medicine ; (12): 804-807, 2011.
Artículo en Inglés | WPRIM | ID: wpr-820053
ABSTRACT
OBJECTIVE@#To evaluate in vitro antimicrobial and antioxidant activities of methanolic extract of Jasminum humile (J. humile) leaves extract.@*METHOD@#Methanolic extract of J. humile was evaluated for its antimicrobial activity by using agar well diffusion method & their possible antioxidant assay by two complementary test systems, namely DPPH and hydrogen peroxide scavenging activity. These various antioxidant activities were compared to standard antioxidants such as ascorbic acid for both the tests.@*RESULTS@#In the DPPH & hydrogen peroxide scavenging activity, the IC(50) value of methanol extract was 70.43 μg/mL & 60.79 μg/mL respectively. Further, the extract showed inhibitory activity for Gram-positive and negative bacteria at different concentrations. The maximum antibacterial activity of extract was exhibited against Staphylococcus aureus (S. aureus) at concentration 50 mg/mL when compared with ciprofloxacin@*CONCLUSIONS@#These results clearly indicate that J. humile is effective in scavenging free radicals and has the potential to be a powerful antioxidant. Thus, the results obtained in the present study indicate that J. humile leaves extract could be considered as a potential source of natural antioxidants and that could be used as an effective source against bacterial diseases.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Picratos / Ácido Ascórbico / Compuestos de Bifenilo / Extractos Vegetales / Ciprofloxacina / Química / Hojas de la Planta / Concentración 50 Inhibidora / Jasminum Límite: Humanos Idioma: Inglés Revista: Asian Pacific Journal of Tropical Medicine Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Picratos / Ácido Ascórbico / Compuestos de Bifenilo / Extractos Vegetales / Ciprofloxacina / Química / Hojas de la Planta / Concentración 50 Inhibidora / Jasminum Límite: Humanos Idioma: Inglés Revista: Asian Pacific Journal of Tropical Medicine Año: 2011 Tipo del documento: Artículo