Meta analysis of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of populations in East Asia
Asian Pacific Journal of Tropical Medicine
;
(12): 483-487, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-820666
ABSTRACT
OBJECTIVE@#To assess the relation between XRCC3 Thr241Met polymorphism and lung cancer susceptibility of populations in East Asia.@*METHODS@#Related studies of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of populations in East Asia were collected through searching the Pubmed, Embase Library, SPRINGER, CNKI and CSSCI.@*RESULTS@#According to the entry criteria, there were 8 case-control studies in the assessing system and there were 6 321 study cases, including 3 215 patients with lung cancer and 3 106 cases without cancers. Meta analysis results showed the combined OR value of the ratio of genotype Thr/Met+Met/Met and Thr/Thr was 1.03 (95%CI 0.89-1.20) (P>0.05).@*CONCLUSIONS@#XRCC3 Thr241Met polymorphism may not related to lung cancer susceptibility of populations in East Asia. Allele 241Met did not increase the risk of lung cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo Genético
/
Epidemiología
/
Predisposición Genética a la Enfermedad
/
Proteínas de Unión al ADN
/
Asia Oriental
/
Genética
/
Neoplasias Pulmonares
Tipo de estudio:
Estudio observacional
/
Revisiones Sistemáticas Evaluadas
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Asian Pacific Journal of Tropical Medicine
Año:
2014
Tipo del documento:
Artículo
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