Expression changes of S100 family proteins and their functional significances in renal cancer / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 223-230, 2020.
Article
en Zh
| WPRIM
| ID: wpr-821087
Biblioteca responsable:
WPRO
ABSTRACT
@#Renal cell carcinoma is a common type malignant tumor of the urinary system. The global incidence of renal cancer is 2. 2%. S100 proteins are involved in the regulations of proliferation, differentiation, apoptosis, and Ca2+ homeostasis, etc. S100 proteins are often closely associated with tumor progression. This review lists the expression changes of S100s and their functional significances in renal cancers, providing a new direction for the researches and treatments of renal cancer. The interpretation of S100 in the regulation of VHL/HIF signaling pathways should be a future direction.
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WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Año:
2020
Tipo del documento:
Article