Research progress in Immunescore system in tumor prognosis / 医学研究生学报

ABSTRACT

Tumor is one of the most common diseases threatening human health, morbidity and mortality of which are on the rise. At present, TNM staging system is widely used to evaluate the prognosis of patients, but this system has been challenged. Emerging evidence shows that post-operative patients with same TNM stage may exhibit significantly discrepant survival. New classification methods based on tumor cell type, molecular pathways, mutation status and tumor gene expression only exhibit moderate prediction accuracy and limited clinical use. Recently, various studies have shown that Immunoscre can predict the prognosis of patients with colorectal cancer more accurately and guide personalized therapy better. This article introduces the establishment and development of Immunoscore system, and reviews the value, advantages and problems in guiding treatment.