Diagnosis and treatment strategies for inflammatory bowel disease with concomitant biliary diseases / 临床肝胆病杂志

ABSTRACT

Inflammatory bowel disease (IBD) is a series of non-specific chronic inflammatory diseases, including ulcerative colitis and Crohn’s disease. Besides gastrointestinal symptoms, IBD patients often have extraintestinal symptoms which may involve various systems such as the skeleton and muscle, skin, eyes, liver and gallbladder, pancreas, nerves, urogenital system, lungs, heart, and blood. Biliary diseases are extraintestinal manifestations of IBD and mainly include primary sclerosing cholangitis, IgG4-associated sclerosing cholangitis, primary biliary cirrhosis, and cholelithiasis. Biliary diseases may manifest as transient abnormal liver function in asymptomatic patients and even life-threatening liver failure, and different biliary diseases may have different treatment methods and prognoses and thus require careful differential diagnosis. This article reviews biliary diseases in IBD patients, in order to help clinicians get familiar with the clinical manifestations and diagnosis and treatment strategies for biliary diseases in IBD patients.