Echocardiographic evaluation of right ventricular function in aged patients with chronic obstructive pulmonary disease／ / 心血管康复医学杂志

ABSTRACT

To explore evaluation of echocardiography (ECG) for early change of right ventricular function in aged patients with chronic obstructive pulmonary disease (COPD).Methods :A total of 45 aged patients with mild‐moderate stable COPD were selected as COPD group , and another 45 healthy volunteers were regarded as healthy control group .Two‐dimensional ultrasound and Doppler ultrasound indexes were measured and compared be‐tween two groups ,and their correlation were analyzed .Results :Compared with healthy control group ,there were significant rise in right ventricular transverse diameter [RVTD ,(28.03 ± 2.83) mm vs.(37.55 ± 5.44) mm] ,right ventricular wall thickness [RVWT ,(4.79 ± 0.44) mm vs.(5.04 ± 0.66) mm] ,right ventricular myocardial per‐formance index [RVMPI , (0.38 ± 0.06 ) vs .(0.54 ± 0.12 )] , tricuspid regurgitation pressure gradient [TRPG , (9. 50 ± 1. 93) vs.(36.87 ± 6.27 )] , tricuspid diastolic peak E／tissue Doppler tricuspid annular diastolic e′[E／e′, (4. 24 ± 0. 72) vs.(6.48 ± 1. 51)] and significant reductions in right ventricular fraction area change [FAC ,(53. 35 ± 5.41)% vs.(40.21 ± 7.24)%] ,tricuspid annular plane systolic excursion [TAPSE ,(20. 78 ± 2.64) vs.(14. 15 ± 2.44)] ,tricuspid early／late diastolic peak flow velocity [E／A , (1.17 ± 0.19 ) vs.(0.73 ± 0.14 )] , and tissue Doppler tricuspid annular systolic peak velocity [DTIs′,(13. 71 ± 1.25) vs.(12.92 ± 1. 70)] in COPD group , P＜0.05 or ＜0.01. Pearson correlation analysis indicated that TRPG was significant positively correlated with RVTD , RVMPI and RVWT ( r＝0. 440～0.830 , P＜0. 01 all) ,and significant inversely correlated with FAC ,TAPSE and DTIs＇( r＝ －0.615～ －0.561 , P＝0.001 all).Conclusion :RVTD ,FAC ,TAPSE ,tricuspid E／A ,E／e＇,RVMPI and TRPG etc .can be used to assess early change of right ventricular function .