Laparoscopic cholecystectomy with or without percutaneous transhepatic gallbladder drainage for acute severe cholecystitis:a meta-analysis / 中华肝胆外科杂志

ABSTRACT

0bjective To compare laparoscopic cholecystectomy(LC)with or without percutane-ous transhepatic gallbladder drainage(PTGD)for acute severe ch01ecystitis.Methods According to the predefined inclusion and exclusion criteria.23 articles were selected for this meta.analysis.A1l patients were treated with LC with or without PTGD.A meta-analysis was used to analyze the clinical efficacy.Results Compared with LC.a11 the surgical indicators of LC with PIGD were significantly better than LC alone(all P≤0.05),including the operation time95％CI(-27.24,-9.27);intraoperative blood loss95％CI(-50.25,-40.19);postoperative hospital stay95％CI(-3.63,-O.64);rates of conversion to open abdomenOR=0.48,95％CI(0.32.0.74);rates of incision infectionOR=0.49,95％CI(0.25,O.99);drainage tube indwelling time95％CI(-2.07,-1.19);gastrointestinal function recovery time95％CI(-1.73,-0.77);rates of bile leakageOR=0.23,95％CI(0.12,0.44);and rates of compli-cationsOR=0.36.95％CI(0.27,0.48).Conclusion Compared with LC alone,PTGD+LC is the preferred treatment for acute severe cholecystitis.