Research advances in conversion therapy for primary liver cancer / 临床肝胆病杂志

ABSTRACT

Radical hepatectomy and liver transplantation are the best choices to improve the long-term prognosis of patients with primary liver cancer; however, most of the patients in China have lost the opportunity for surgical treatment at the time of confirmed diagnosis. Therefore, conversion therapy has become a research hotspot in improving the survival rate of patients with advanced liver cancer. This article briefly describes the evaluation of conversion therapy for liver cancer and summarizes the current conversion treatment regimens for unresectable liver cancer. With the deepening of the understanding of primary liver cancer and individualized treatment, the group of precise treatment combined with multidisciplinary diagnosis and treatment develops the regimens for individualized conversion therapy, which is considered to effectively improve the surgical resection rate, treatment outcome, and long-term prognosis of patients with advanced liver cancer.