Role of pyroptosis in the pathogenesis of acute pancreatitis / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 1905-1908, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-825055
ABSTRACT
Acute pancreatitis (AP) is a common gastrointestinal disease and may lead to local complications and even multiple organ failure, and the pathogenesis of AP involves self-digestion of trypsin, inflammatory response, and microcirculation disturbance. This article introduces the role of pyroptosis in the pathogenesis of AP and briefly describes the activation pathway of pyroptosis, inflammasome, and the mechanism of action of effector molecules in inducing damage to the pancreas and extra-pancreatic organs. It is believed that the regulation of pyroptosis plays an important role in the pathogenesis of AP, which provides new ideas for the prevention and treatment of AP.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Journal of Clinical Hepatology
Año:
2020
Tipo del documento:
Artículo
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