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Research progress on small molecule inhibitors of coronaviruses / 药学实践杂志
Journal of Pharmaceutical Practice ; (6): 385-397, 2020.
Artículo en Chino | WPRIM | ID: wpr-825613
ABSTRACT
Coronavirus infection seriously threatens human health. There is no specific medication or vaccine so far. In recent years, domestic and foreign researchers have developed a variety of small-molecule inhibitors against the ligand S protein, RdRp, PLpro and 3CLpro of three highly pathogenic coronavirus, SARS-CoV,MERS-CoVSARS-CoV-2. This article reviews the characteristics of these coronaviruses, action targets, small molecule inhibitors, and structure-activity relationships.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Pharmaceutical Practice Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Pharmaceutical Practice Año: 2020 Tipo del documento: Artículo