An updated systematic review of Zika virus-linked complications
Asian Pacific Journal of Tropical Medicine
; (12): 1-8, 2018.
Article
en En
| WPRIM
| ID: wpr-825809
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To determine the breadth of Zika virus (ZIKV)-associated brain anomalies in neonates and adults.Methods:Systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement using electronic databases ScienceDirect, Pubmed, Medline, Scopus, and Global Health Library. Only those research articles, case studies, case-control studies, case-cohort studies, cross-sectional studies, and organizational survey reports were included in the study that reported any fetal outcomes for pregnant women who had infected with ZIKV during the gestational period and ZIKV-related neurological complications in adults as well.Results:Out of total 72 retrieved articles, 50 met the inclusion criteria. We estimated a significant increase in incidence of neural abnormalities such as Guillain-Barre syndrome and microcephaly in the regions that are experiencing ZIKV outbreaks. Other neurological malformations found in ZIKV patients include hydrancephaly/hydrops fetalis, myasthenia gravis, meningoencephalitis and myelitis.Conclusion:Our systematic analysis provides the broad spectrum of neurological malformations in ZIKV infected patients and these data further support the causal link of ZIKV with neurological disorders.
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WPRIM
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
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Systematic_reviews
Idioma:
En
Revista:
Asian Pacific Journal of Tropical Medicine
Año:
2018
Tipo del documento:
Article