Research progress in markers of limbal stem cells / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 2064-2069, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-829706
ABSTRACT
@#The continuous proliferation and differentiation of limbal stem cells(LSCs)maintain the integrity and homeostasis of the corneal epithelium, which plays an important role in protecting the cornea and maintaining corneal transparency. Currently limbal stem cell deficiency(LSCD)is one of major causes of blindness in corneal diseases, and transplantation of LSCs is the hot therapeutic option. The effectiveness of transplantation mainly depends on the proportion of LSCs to the total transplanted cells, so it is very important to clearly identify LSCs. There are many markers of LSCs, but their specificity is controversial. Therefore, one of the main challenges in LSCs transplantation is the lack of definitive cell markers. In this paper, the latest research progress of LSCs markers is reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Eye Science
Año:
2020
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS