A Case of Type I membranoproliferative Glomerulonephritis Associated with Cellulitis on Lower Leg / 대한신장학회잡지

ABSTRACT

Membranoproliferative glomerulonephritis(MPGN) is a morphologic entity and characterized by several pathologic feature. MPGN is classified into a primary (or idiopathic) and secondary forms. We report a case of type I MPGN associated with cellulitis on pathologic feature. MPGN is classified into a primary (or idiopathic) and secondary forms. We report a case of type I MPGN associated with cellulitis on lower leg. He was admitted due to ingrowing nail complicated by surrounding cellulitis and edema. Chraracteristically, hematuria and proteinuria(3.2gm/ day) were noted. We couldn't find any secondary causes', ANA, cryoglobulin, HBs Ag and RA factor were negative. Renal pathologic findings showed double-contoured basement membrane, electron-dense material infiltration and mesangial proliferation. This findings were concordant with type I MPGN and we treated with antibiotics and supportive care. During follow-up, skin lesion, proteinuria and hematuria were resolved and he readmitted in purpose of control renal biopsy, We observed resolution of previous abnormal findings other than mesangial proliferation. This case was considered as type I MPGN associated with cellulitis on lower leg.