Long noncoding RNAs in ovarian cancer: Progress in mechanisms and the emerging landscape / 第二军医大学学报

ABSTRACT

Long non-coding RNAs (IncRNAs) are a class of RNA molecules with more than 200 nucleotides that function as RNAs with little or no protein-coding capacity. They maintain the normal physiological functions of cells and are involved in the development and progression of the tumor. Growing research suggests that lncRNAs are independent prognostic factors affecting the overall survival and disease free survival of ovarian cancer and are closely related to the development and progression of tumors. This review summarized the recent progress in the relationship between lncRNAs and ovarian cancer, hoping to provide reference for the prevention, diagnosis, and therapy of ovarian cancer.