Absorbable hemostatic materials: Safety and clinical application / 第二军医大学学报

ABSTRACT

This paper reviews the composition, mechanisms, safety and clinical application of major absorbable hemostatic materials, including oxidized cellulose, oxidized regenerated cellulose, thrombin sealants, fibrin glue,collagen, gelatin, α-cyanoacrylate sealants, bovine albumin and gluteraldehyde, chitosan-based hemostatic agents and microporous polysaccharide. Special attention was paid to the relationship between different absorbable hemostatic agents and the blood coagulation mechanism. We also discussed the future development of absorbable hemostatic agents.