Anti-LGI1 Limbic Encephalitis Presented with Atypical Manifestations
Experimental Neurobiology
;
: 337-340, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-84001
ABSTRACT
Anti-leucine-rich glioma inactivated-1 (LGI1) limbic encephalitis (LE) is a rare neurological disorder that has a subacute course of progressive encephalopathy and fasciobrachial dystonic seizures. We report a patient with anti-LGI1 LE that presented with atypical manifestations that complicated the diagnosis. A 62-year-old woman presented with a chronic course of memory disturbance and a subsequent relapse with an altered mental status after 10 months. The patient reported frequent chest pain of squeezing and dull nature, typically lasting 10-30 seconds. The chest pain was related to partial seizures, which were confirmed by video-EEG monitoring. Anti-LGI1 antibody was identified in serum and CSF. The patient's symptoms improved by immune modulation treatment. Patients with anti-LGI1 LE can experience atypical partial seizures, and a chronic relapsing course. Clinical suspicions and video-EEG monitoring are helpful for the early diagnosis and effective immune modulation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recurrencia
/
Convulsiones
/
Dolor en el Pecho
/
Encefalitis Límbica
/
Diagnóstico Precoz
/
Diagnóstico
/
Glioma
/
Memoria
/
Enfermedades del Sistema Nervioso
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Experimental Neurobiology
Año:
2013
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS