Significance of colonoscopy in screening of family members from familial adenomatous polyposis families / 第二军医大学学报

ABSTRACT

Objective: To study the diagnostic value of colonoscopy in screening of family members of a familial adenomatous polyposis (FAP) family. Methods: The colonoscopic findings of 38 sibs from 23 FAP families (1985-2002) were retrospectively studied. The diagnostic value of colonoscopy for screening FAP in FAP families was analyzed through determining the amount, morphology, and pathology of polyps. Results: Sixteen of the 38 sibs were found to have polypous growths, the positive screening rate being 42.1%; of the 16 cases of polypous growths, one was found to be severe atypical proliferation. The left hemicolon and rectum had dense polyps. Conclusion: Colonoscopy is a safe and reliable screening examination in sibs of FAP families.