Pharmacological effects and clinical application of tetrandrine: research advances / 国际药学研究杂志

ABSTRACT

Tetrandrine(TET)is a bisbenzyl isoquinoline alkaloid extracted from the plant Stephania tetrandra. TET is one of the important active ingredients of S.tetrandra, showing pharmacological effects mainly on the circulatory, respiratory and locomotor systems, such as the anti- inflammatory, anti-tumor, anti-arrhythmia, anti-hypertensive, anti-silicosis and fibrosis effect, and thus has a high clinical application value. This article reviews research achievements of the pharmacological effects, action mechanisms, dosage forms and clinical applications of TET, in order to provide reference for related research.