Several stereogenic problems regarding structural elucidation of marine natural products / 国际药学研究杂志

ABSTRACT

During the structural elucidation of natural products, one of the key steps is attributed to the solution of configuration including chiral carbons, axial and planar asymmetry. Stereogenic assignment is an essential work involved in natural product chemistry, while identification of stereogenic centers may be helpful to recognize the structure related to target function. Modern spectroscopic technology provided a reliable tool for the configurational assignment. In this paper, we intend to summarize part of our work regarding the application of extensive spectroscopic methods for the determination of the absolute configurations of marine-derived natural products.