Research progress on mechanism of chinonin in treatment of neurodegenerative diseases / 中草药

ABSTRACT

Chinonin is a natural compound with C-glycoside and xanthones, possessing several biological effects, such as anti-oxidation, anti-inflammation, improving mitochondrial bioenergy and ameliorating cognitive deficits. Moreover, chinonin can exert its neuroprotective effect on the central nervous system through the blood-brain barrier. This review discusses the pathophysiological mechanisms of Alzheimer’s disease and Parkinson’s disease in neurodegenerative diseases, for the purpose of investigating the underlying mechanisms of chinonin in neuroprotection and providing the reference for its further research and application.