Cervical cancer with intraspinal epidural space metastasis: A case report and literature review / 肿瘤

ABSTRACT

Objective: To introduce the diagnosis and treatment of a patient suffering from cervical cancer with intraspinal epidural space metastasis, aiming to provide the further insight into the metastasis of advanced cervical cancer for clinicians. Methods: A middle-aged female patient with multiple metastasis of advanced cervical cancer was reported. The diagnosis and treatment process of this case was analyzed, and the related literatures were reviewed. Results: A 41 years old female was admitted to the hospital in July 2019 owing to the acratia and numbness of double lower limbs for 1 week. Moreover, the patient suffered from cervical cancer and had been operated for more than 4 years. According to her medical history and the test of contrast-enhanced MR of thoracolumbar segment, the lesion located in the intraspinal epidural space on the height of T5-7 vertebral body was considered to be metastatic cancer. To alleviate the symptom, the patient received the palliative operation. The mass obtained from the intraspinal epidural space by operation was pathologically confirmed as the cervical cancer metastasis. The myodynamia of double lower limbs increased 1 month after operation. However, the patient died from multiple organ failure due to advanced cancer in December 2019. Conclusion: The advanced cervical cancer generally invades the organs by hematogenous metastasis, but the intraspinal epidural metastasis is very rare and the prognosis is very poor. Therefore, it should be highly suspected that cervival cancer may be accompanied by brain or intraspinal epidural metastasis if the patient has cervical cancer history and the symptoms of nerve system.