Progress in research on the reciprocal effects between tumor and nerve fibers / 肿瘤

ABSTRACT

Development and progression of tumor is regarded as a result of mutual interaction between tumor cells and their surrounding microenvironment. As one of the most important regulation system of the human body, the nervous system is inevitably involved. It is confirmed that the regenerated nerve fibers are distributed in gastric cancer. On one hand, tumor cells can release some factors to promote nerve regeneration, which is similar to neoangiogenesis and lymphangiogenesis; on the other hand, tumor cells can exploit the advantage of the factors released by newborn nerves to influence biological behaviors of tumor. The mechanism of relationship between nerve system and tumor needs further study, which may undoubtedly enrich the theory of tumor biology and provide a new way for prevention and treatment of tumor.