Advances in the treatment of gastric cancer targeting PI3K/Akt/mTOR pathway / 肿瘤
Tumor
;
(12): 191-196, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-848815
ABSTRACT
Phosphoinositide-3 kinase (PI3K)/protein kinase B (PKB/AKT)/mammalian target of rapamycin (mTOR) pathway is associated with cell proliferation, survival and migration. It plays an important role in the process of tumorgenesis. As a kind of antitumor target, numerous researches have focused on this pathway in recent years. This review summarizes the advances in regulation, protein expression and targeted therapy of PI3K-AKT/mTOR pathway for gastric cancer, and predicts the hot spots of this pathway in gastric cancer in the future studies. Copyright © 2014 by TUMOR.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Tumor
Año:
2014
Tipo del documento:
Artículo
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