Diagnosis and treatment of central neurocytoma: A report of 7 cases with review of the literature / 肿瘤

ABSTRACT

Objective: To analyze the imaging findings, diagnosis and treatment of central neurocytoma. Methods: The clinical information of 7 cases of central neurocytoma in Second Hospital of Hebei Medical University from January 2005 to March 2013 was retrospectively analyzed. The surgical experience was summarized, and the related literatures were reviewed. Results: Of 7 cases, 3 were females and 4 were males; 6 had tumor in anterior 2/3 of the ventricle, 5 originated from septum pellucidum around monro foramen, 1 originated from lateral ventricular wall. The MRI showed that the lesions were mostly hypointense and displayed mixed signals on T1WI images, mainly hypointense and slightly hyperintense signals on T2WI images; most of neurocytomas showed heterogeneous enhancement on dynamic contrast-enhanced MRI images. Six cases underwent gross total resection, 1 case underwent subtotal resection. Two cases received postoperative radiotherapy, 1 case received adjuvant chemotherapy. One case died postoperatively in hospital. Five cases were followed-up, and 1 case was lost to follow-up. The follow-up time was from 15 to 25 months. Four cases had satisfying prognosis, 1 case had hemiplegic paralysis, and no cases had recurrent tumor. Conclusion: Microneurosurgery is the best treatment for central neurocytoma, mastering the technique and key points of operation can achieve significant clinical effectiveness and improve the prognosis. Copyright © 2013 by TUMOR.