Diagnosis and treatment of primary plasma cell leukemia / 肿瘤

ABSTRACT

Primary plasma cell leukemia (PPCL) is a rare, highly aggressive plasma cell disease characterized with a poor prognosis and a low response rate to conventional therapy. It occurs de novo in the absence of a prior history of plasma cell myeloma. Recently, the use of novel drugs such as bortezomib and the approaches such as stem cell transplantation may improve the outcomes of PPCL. This review summarizes the diagnosis and treatment of PPCL in order to provide reference information for clinical practice. Copyright© 2012 by TUMOR.