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The diagnostic values of MRI, enhanced CT and PET-CT in detecting skull base invasion of nasopharyngeal carcinomas: A comparative study / 肿瘤
Tumor ; (12): 795-798, 2008.
Artículo en Chino | WPRIM | ID: wpr-849306
ABSTRACT

Objective:

To compare the diagnostic values of magnetic resonance imaging (MRI), enhanced computed tomography (CT), and positron emission tomography (PET)-CT using 18F-fluoro-2-deoxyglucose (FDG) in detecting skull base invasion of nasopharyngeal carcinoma (NPC) and provide the evidence for differentiated diagnosis of the skull base invasion of NPC.

Methods:

The fifty seven patients were scanned by MRI, enhanced CT, and PET-CT. The three imaging examinations were finished within 20 days. The diagnosis standards were based on histopathologic findings or clinical and imaging follow-up results within 6 months. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of the three scanning technologies were compared.

Results:

For detecting skull base invasion of NPC, the sensitivity of enhanced CT, MRI, and PET-CT were 68.18%, 84.09%, and 97.67%, respectively; the specificity were 76.92%, 69.23%, and 57.14%, respectively; the accuracy were 70.18%, 80.70%, and 87.72%, respectively; PPV were 90.90%, 90.24%, and 87.50%, respectively; NPV were 41.67%, 56.25%, and 88.89%, respectively. PET-CT was better than enhanced CT in sensitivity, accuracy, and NPV (P <0.05). It was also better than MRI in sensitivity and NPV (P <0.05).

Conclusion:

Among three imaging technologies,PET-CT has obvious advantage in detecting skull base invasion of NPC patients, especially for new patients.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio diagnóstico / Guía de Práctica Clínica / Estudio pronóstico Idioma: Chino Revista: Tumor Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio diagnóstico / Guía de Práctica Clínica / Estudio pronóstico Idioma: Chino Revista: Tumor Año: 2008 Tipo del documento: Artículo