Expressions of heparanase and CD44v6 in osteosarcoma tissues and their correlations / 肿瘤
Tumor
;
(12): 817-820, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-849497
ABSTRACT
Objective:
To study the expression of heparanase and CD44v6 in osteosarcoma and analyze the correlation between them.Methods:
The expressions of heparanase and CD44v6 in human osteosarcoma were detected by immunohistochemical staining.Results:
The positive rates of heparanase and CD44v6 protein in osteosarcoma tissues were significantly higher in osteosarcoma tissues than in osteochondroma (79.6% vs 20.0% and 55.1% vs 25.0%, P < O. 05). Expressions of heparanase and CD44v6 had positive correlation (r=0.663, P < 0.001). Both of them were closely associated with clinical stage and metastasis of osteosarcoma.Conclusion:
Overexpressions of heparanase and CD44v6 in human osteosarcoma may stimulate the adhesion, invasion, and metastasis of osteosarcoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Tumor
Año:
2007
Tipo del documento:
Artículo
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