Evaluation of methodological and reporting quality of the clinical practice guidelines on Henoch-Schonlein purpura by AGREEII and RIGHT / 解放军医学杂志

ABSTRACT

Objectives To evaluate the current methodological and reporting quality of clinical practice guidelines on Henoch-Schonlein purpura (HSP) for providing the reference for the development of high quality HSP clinical practice guidelines. Methods Databases as PubMed, NICE, Medlive, WHO, Wanfang Data, CNKI, VIP and CBM were electronically searched to collect the clinical practice guidelines on HSP from Jan. 2010 to Dec. 2019. Two reviewers independently screened literature, extracted data and evaluated the methodological and reporting quality by using appraisal of guidelines research and evaluation Ⅱ (AGREEⅡ) and Reporting Items for Practice Guidelines in Healthcare (RIGHT) tools, respectively. Results A total of five HSP clinical practice guidelines were included, three of which are evidence-based guidelines, and the remaining two are based on expert consensus; and three guidelines for clinical practice in traditional Chinese medicine and two for western medicine were selected for evaluation. The AGREEⅡevaluation showed that the HSP guidelines had higher scores in terms of "scope and purpose" (67.8%) and "clarity of presentation" (57.2%), while the average scores were lower in another four areas, i.e. stakeholder involvement (25.6%), rigor of development (33.3%), applicability (9.2%) and editorial independence (43.3%). The RIGHT evaluation showed that, for five HSP guidelines, the corresponding reporting rates of "basic information", "background", "evidence", "recommendations", "review and quality assurance", "funding and conflict of interest statement and management" and "other information" accounted for 0%, 20%, 20%, 0%, 0%, 0% and 0%. A total of 75 recommendations of HSP clinical practice guidelines were classified into 7 for the diagnosis and 68 for the treatment. Conclusions The methodological and reporting quality of HSP clinical practice guidelines are still to be improved. The guidelines should be developed in strict accordance with AGREEⅡand RIGHT.