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Advances in long non-coding RNA in chemotherapeutic resistance of hepatocellular carcinoma / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army ; (12): 547-553, 2020.
Artículo en Chino | WPRIM | ID: wpr-849717
ABSTRACT
Hepatocellular carcinoma (HCC), as a global malignant tumor with high morbidity and mortality, has seriously endangered human health. In the treatment of HCC, chemotherapy resistance is the knotty problem. Long non-coding RNA (lncRNA), as a new multifunctional molecule with complex mechanisms, plays a role in the biological processes of HCC, such as development, progression, invasion and migration, and participates in the complex mechanism of drug resistance through abnormal regulation of gene expression. In this paper, to seek for the new method for solving the chemotherapeutic resistance of HCC based on the research of lncRNA, the effect and mechanism of lncRNA on chemotherapeutic resistance of HCC were summarized.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Medical Journal of Chinese People's Liberation Army Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Medical Journal of Chinese People's Liberation Army Año: 2020 Tipo del documento: Artículo