Research progress on Ziziphi Spinosae Semen and Ziziphi Mauritianae Semen and Q-marker predictive analysis / 中草药

ABSTRACT

Both Ziziphi Spinosae Semen (ZSS) and Ziziphi Mauritianae Semen (ZMS) were derived from the dried seeds of the genus Ziziphus. The classical application of ZSS and ZMS is supplementing the liver, quieting the heart, arresting the sweat, and promoting the production of the body fluids. Alone or in combination with other herbs, ZSS is the most frequently used herb for treating insomnia. In addition, ZMS was used widely in Yunnan as local used medicine. Recently, the reduction of the wildlife resources of ZSS and shortage of market supply resulted in the adulteration of ZSS by substituting with ZMS. In this paper, the difference was contrasted between ZSS with ZMS by summarized the three aspects of herbal research, chemical composition, and pharmacological action. The original source, efficacy, in vivo process, and the traditional property were probed in order that the Q-markers of ZSS were predicted, based on the concept of Q-marker. This research will provide a theoretical basis for the improvement of the quality standard of ZSS.