Research progress in Atractylodes macrocephala and predictive analysis on Q-marker / 中草药

ABSTRACT

To study the quality marker (Q-marker) of Atractylodes macrocephala based on the concept, standard, and research model of Q-marker. The chemical constituents of A. macrocephala were identified by UPLC-Q-TOF-MS/MS. The source and specificity of chemical constituents were confirmed by analyzing biosynthetic pathway and component specificity. The major effective components were clarified through efficacy, drug property, and correlation analysis of chemical constituents. The possible Q-markers of A. macrocephala are estimated based on the results of the study.