Study on triterpenoid glycosides from roots of Clematis manshurica / 中草药

ABSTRACT

Objective: To study the chemical constituents from the roots of Clematis manshurica. Methods: Ten compounds were separated and purified by silica gel, Sephadex LH-20, and preparative HPLC. The structures were identified by physicochemical properties and spectral analyses. Results: A total of ten oleanane-type triterpenoid saponins were isolated and identified as clematomandshurica saponin L (1), clematichinenoside A (2), clematochinenoside F (3), clematernoside A (4), clematichinenoside B (5), clematichinenoside C (6), clematomandshurica saponin B (7), clematomandshurica saponin D (8), clematomandshurica saponin C (9), and huzhangoside B (10), respectively. Conclusion: Compound 1 is a new oleanane-type triterpenoid glycoside, and compounds 2-6 are isolated from this plant for the first time.